Quinolines and derivatives

Aromatic organic heterocyclic compounds that contain a benzene ring fused with a six-membered ring that contains one nitrogen atom and five carbon atoms. Includes compounds that are derived from quinolines.

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511 – 525 of 4,236 results

511

Medchemexpress LLC 4-quinolinecarboxylic acid, 7-bromo- | 31009-04-8 | MFCD11108751 | 96.1% | 252.06 | C10H6BrNO2 | 250 MG

7-Bromoquinoline-4-carboxylic acid is an aromatic heterocyclic carboxylic acid used as an intermediate and building block in organic synthesis, particularly in medicinal chemistry and materials research. It is typically handled as a solid reagent and supplied with batch documentation for quality control.

Used as an intermediate in organic and medicinal chemistry.
HPLC purity 96.1%.
Molecular formula C10H6BrNO2; molecular weight 252.06.
Appearance: gray to brown solid.
Storage: powder -20°C (stable 3 years) or 4°C (2 years); in solvent -80°C (6 months) or -20°C (1 month).
Batch certificate of analysis and safety data sheet available.

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512

eMolecules 1447607-02-4 | ChemScene | Ethyl 7-aminoquinoline-2-carboxylate | 100mg | 711937895 | CS-0149239 | MFCD25542354 | 216.24 | C12H12N2O2

Ambeed | Fmoc-D-Tle-OH | 5g | 572840678 | A547654 | 198543-64-5 | MFCD00065650 | 353.418 | C21H23NO4

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513

Medchemexpress LLC (2R)-N-[(2S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl]-N'-hydroxy-2-(2-methylpropyl)butamid | 145337-55-9 | 99.4% | 315.41 g/mol | C15H29N3O4 | 100 MG

Ro 31-9790 is a synthetic matrix metalloproteinase (MMP) inhibitor provided for research use. It serves as a biochemical probe to study MMP-related activity in vitro and in cell-based assays. The compound is identified by CAS 145337-55-9 and is characterized by a defined molecular formula and high reported purity.

Acts as a matrix metalloproteinase inhibitor for research applications.
High purity, approximately 99.4%.
Molecular weight 315.41 g/mol; formula C15H29N3O4.
Suitable as a research-grade chemical for biochemical and cell biology studies.
Synonyms and systematic names are available in chemical databases for cross-referencing.

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514

Ambeed AMBEED

5000885102 4-BROMOPYRIDINE-2-CARBAL 10G

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515

Ambeed AMBEED

5000886094 4-CHLORO-7-METHOXYQUINOL 10G

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516

eMolecules 885276-33-5 | Methyl 2,3-dibromo-3,3-difluoropropionate | Combi-Blocks | MFCD07784249 | 281.879 | C4H4Br2F2O2 | 95.000 | COC(=O)C(Br)C(F)(F)Br | 1g | 401041469

Methyl 2,3-dibromo-3,3-difluoropropionate | Combi-Blocks | 885276-33-5 | MFCD07784249 | 281.879 | C4H4Br2F2O2 | 95.000 | COC(=O)C(Br)C(F)(F)Br | 1g | 401041469

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517

Medchemexpress LLC IL-31 Cynomolgus H 10ug | 10ug

IL-31 is a multifunctional cytokine that activates STAT3 through IL-31 heterodimeric receptors (IL31RA and OSMR) and may activate STAT1 and STAT5 IL-31 is known for its involvement in skin immunity where it regulates immune responses IL-31 Protein Cynomolgus (HEK293 His) is the recombinant cynomolgus-derived IL-31 protein expressed by HEK293 with C-His labeled tag

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518

Selleck Chemical LLC JNK-IN-8 S4901-1g

JNK-IN-8 (JNK Inhibitor XVI) is the first irreversible JNK inhibitor for JNK1 JNK2 and JNK3 with IC50 of 4 7 nM 18 7 nM and 1 nM 10-fold selectivity against MNK2 Fms and no inhibition to c-Kit Met PDGFR in A375 cell line

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519

Medchemexpress LLC MI-773 | 1303607-07-9 | 96.3% | 562.50 | 100 MG

MI-773 is a potent MDM2-p53 protein-protein interaction (PPI) inhibitor. It demonstrates high binding affinity against MDM2 and exhibits antitumor activity. An analog, MI-77301, shows even higher binding affinity and more pronounced antitumor activity in various p53 xenograft models.

Potent MDM2-p53 protein-protein interaction (PPI) inhibitor.
High binding affinity against MDM2 (Kd=8.2 nM).
Exhibits antitumor activity.
Analog shows enhanced binding affinity and antitumor activity.
Effective in various p53 xenograft models including osteosarcoma, human prostate, melanoma, colorectal tumor, and human acute lymphoblastic leukemia.

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520

Medchemexpress LLC MEDCHEMEXPRESS LLC

5000746657 ALPELISIB 200MG

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521

Medchemexpress LLC AM095 | 1345614-59-6 | 99.7% | 478.47 | 200 MG

AM095 is a selective LPA1 receptor antagonist known for its potent inhibition of LPA-induced calcium flux in human and mouse LPA1-transfected CHO cells. It demonstrates an exceedingly low IC50 for human (0.025 μM) and mouse (0.023 μM) cells, positioning it as a valuable tool for research involving LPA1 receptor pathways.

Selective LPA1 receptor antagonist.
Potently inhibits LPA-induced calcium flux.
Applicable in studies involving human or mouse LPA1-transfected CHO cells.
Useful for researching LPA1 receptor pathways.

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522

Selleck Chemical LLC Chelerythrine Chloride (NSC 646662) S1292-5mg

Chelerythrine Chloride (NSC 646662 Broussonpapyrine) is a potent selective antagonist of PKC with IC50 of 0 66 M

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523

Medchemexpress LLC Amifostine thiol dihydrochloride | 14653-77-1 | MFCD00460339 | ≥98.0% | 207.16 g/mol | C5H16Cl2N2S | 1 MG

Amifostine thiol dihydrochloride is the dihydrochloride salt of WR-1065, the active thiol metabolite of amifostine. It is supplied as a research reagent and analytical standard for studies of radioprotection, cytoprotection from chemotherapeutic agents, and p53/JNK-dependent signaling.

Protects normal tissues from toxic effects of certain cancer agents.
Activates p53 through a JNK-dependent signaling pathway.
Supplied as a dihydrochloride salt for improved handling and stability.
Provided in small research quantities suitable for analytical and biological studies.

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524

Medchemexpress LLC Bosutinib hydrate | 918639-08-4 | MFCD29920031 | 100.0% | 548.46 g/mol | C26H31Cl2N5O4 | 200 MG

Bosutinib hydrate is a small-molecule dual Src/Abl tyrosine kinase inhibitor supplied as a white to off-white solid for research use. It exhibits low-nanomolar potency against Src and Abl kinases and is intended for biochemical and cell-based studies; supporting documents such as SDS and COA are provided for analytical verification and safe handling.

Dual Src and Abl kinase inhibition at low-nanomolar concentrations.
High reported purity suitable for research applications.
Available in multiple packaging sizes, including 200 MG.
White to off-white solid appearance for easy handling.
Storage and stability guidance provided for solid and solution forms.
COA and SDS available to support quality and safety use.

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525

Medchemexpress LLC Sevabertinib (BAY 2927088) | 2521285-05-0 | 99.9% | 484.93 | 200 MG

Sevabertinib (BAY 2927088) is an orally active and reversible dual EGFR-HER2 inhibitor with potent anticancer activity against lung cancer. It shows significantly reduced activity against HER4.

Orally active and reversible dual EGFR-HER2 inhibitor
Exhibits anticancer activity against lung cancer
Potently inhibits proliferation of isogenic Ba/F3 cells ectopically expressing HER2 exon 20 insertions
Potently inhibits proliferation of isogenic Ba/F3 cells activating HER2 point mutations or putative secondary acquired resistance mutations
Inhibits proliferation of lung cancer cell lines NCI-H1781 and NCI-H2170

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Quinolines and derivatives

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Medchemexpress LLC 4-quinolinecarboxylic acid, 7-bromo- | 31009-04-8 | MFCD11108751 | 96.1% | 252.06 | C10H6BrNO2 | 250 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC (2R)-N-[(2S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl]-N'-hydroxy-2-(2-methylpropyl)butamid | 145337-55-9 | 99.4% | 315.41 g/mol | C15H29N3O4 | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC IL-31 Cynomolgus H 10ug | 10ug Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Selleck Chemical LLC JNK-IN-8 S4901-1g Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC MI-773 | 1303607-07-9 | 96.3% | 562.50 | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC MEDCHEMEXPRESS LLC Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC AM095 | 1345614-59-6 | 99.7% | 478.47 | 200 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Selleck Chemical LLC Chelerythrine Chloride (NSC 646662) S1292-5mg Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Amifostine thiol dihydrochloride | 14653-77-1 | MFCD00460339 | ≥98.0% | 207.16 g/mol | C5H16Cl2N2S | 1 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Bosutinib hydrate | 918639-08-4 | MFCD29920031 | 100.0% | 548.46 g/mol | C26H31Cl2N5O4 | 200 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Sevabertinib (BAY 2927088) | 2521285-05-0 | 99.9% | 484.93 | 200 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More